The Ultimate Guide To megatomi.com
The Ultimate Guide To megatomi.com
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Quickly attain sections as skinny or thick as your application involves, with out worrying about dropping or distorting precious tissue samples.
Megatome is actually a vibrating microtome intended to part a wide number of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform surface area profile, and also small tissue destruction and knowledge loss.
Antibodies might consider months to diffuse by way of only some millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is designed for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and features a unique deflection control system.
SE uses a rotational electric powered discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) all through a porous sample without harming electrically billed buildings in the tissue. This permits 2-four working day clearing of intact organs,
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eFLASH is a quick tissue labeling method which allows for uniform entire-organ staining in twenty rounds of labeling.
The SmartSPIM mild sheet microscope presents unparalleled resolution and acquisition pace all over intact tissue volumes, although its modular design lets you upgrade and personalize person elements.
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Defend avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, guarding specimens for a number of rounds of processing.
Leverage the Apparent+ tissue clearing method, in addition to eFLASH and patented stochastic electrotransport systems, to fast crystal clear and label whole organs. Vital highlights and characteristics include:
Our megatomi.com novel SHIELD tissue preservation approach kinds intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.